Gene name: PI4KB
Protein name: Phosphatidylinositol 4-kinase beta
List of molecules and drugs that interact with protein Q9UBF8
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q9UBF8_093 | 093 | DB06836 | 6852167 | CHEMBL1229535 | N-(5-(4-CHLORO-3-(2-HYDROXY-ETHYLSULFAMOYL)- PHENYLTHIAZOLE-2-YL)-ACETAMIDE | inhibitor | IC50(nM) = 19.0 |
| 2 | Q9UBF8_3K7 | 3K7 | n/a | 91757958 | CHEMBL3426603 | 6-chloro-3-(3,4-dimethoxyphenyl)-2-methylimidazo[1,2-b]pyridazin-8-amine | n/a | |
| 3 | Q9UBF8_5S8 | 5S8 | n/a | 137348395 | n/a | ~{N}-[5-[3-[[(4-hydroxyphenyl)amino]-bis(oxidanyl)-$l^{4}-sulfanyl]-4-methoxy-phenyl]-4-methyl-1,3-thiazol-2-yl]cyclopentanecarboxamide | n/a | |
| 4 | Q9UBF8_5W3 | 5W3 | n/a | 123131775 | CHEMBL3889874 | ~{N}-[2-[[6-chloranyl-3-[3-(2-hydroxyethylsulfamoyl)-4-methoxy-phenyl]-2-methyl-imidazo[1,2-b]pyridazin-8-yl]amino]ethy l]ethanamide | n/a | |
| 5 | Q9UBF8_5W6 | 5W6 | n/a | 123131773 | CHEMBL3902513 | ~{N}-[2-[[6-chloranyl-3-[3-[4-(hydroxymethyl)piperidin-1-yl]sulfonyl-4-methoxy-phenyl]-2-methyl-imidazo[1,2-b]pyridazin-8-yl]amino]ethyl]ethanamide | n/a | |
| 6 | Q9UBF8_5W7 | 5W7 | n/a | n/a | n/a | ~{N}-[2-[[3-[3-[(4-azanylcyclohexyl)sulfamoyl]-4-methoxy-phenyl]-6-chloranyl-2-methyl-imidazo[1,2-b]pyridazin-8-yl]amino]ethyl]ethanamide | n/a | |
| 7 | Q9UBF8_5W8 | 5W8 | n/a | 123131776 | n/a | ~{N}-[2-[[6-chloranyl-3-[4-methoxy-3-[[(2~{R})-1-oxidanylbutan-2-yl]sulfamoyl]phenyl]-2-methyl-imidazo[1,2-b]pyridazin-8-yl]amino]ethyl]ethanamide | n/a | |
| 8 | Q9UBF8_5W9 | 5W9 | n/a | 123131772 | CHEMBL3923414 | ~{N}-[2-[[6-chloranyl-3-(4-methoxy-3-morpholin-4-ylsulfonyl-phenyl)-2-methyl-imidazo[1,2-b]pyridazin-8-yl]amino]ethyl]ethanamide | n/a | |
| 9 | Q9UBF8_ATP | ATP | DB00171 | 5957 | CHEMBL14249 | ADENOSINE-5'-TRIPHOSPHATE | n/a | |
| 10 | Q9UBF8_BQR | BQR | n/a | 112499905 | CHEMBL4129665 | N~2~-[7-(3,4-dimethoxyphenyl)quinoxalin-2-yl]-N-methylglycinamide | n/a | |
| 11 | Q9UBF8_EMW | EMW | n/a | 76282073 | CHEMBL4211181 | (3~{S})-4-(6-azanyl-1-methyl-pyrazolo[3,4-d]pyrimidin-4-yl)-~{N}-(4-methoxy-2-methyl-phenyl)-3-methyl-piperazine-1-carboxamide | n/a | |
| 12 | Q9UBF8_GDP | GDP | DB04315 | 8977;5280316;135398619; | CHEMBL384759 | GUANOSINE-5'-DIPHOSPHATE | n/a | |
| 13 | Q9UBF8_GSP | GSP | DB01864 | 37792;444121;5280465;135398675;135450576; | CHEMBL1204628 | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE | n/a | |
| 14 | Q9UBF8_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 15 | Q9UBF8_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor |