Gene name: PARP2
Protein name: Poly [ADP-ribose] polymerase
List of molecules and drugs that interact with protein Q9UGN5
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q9UGN5_09L | 09L | DB09074 | 23725625 | CHEMBL521686 | 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one | inhibitor | |
| 2 | Q9UGN5_1WI | 1WI | n/a | 146659481 | CHEMBL5406119 | 1-[[4-fluoranyl-3-(3-oxidanylidene-4-pentan-3-yl-piperazin-1-yl)carbonyl-phenyl]methyl]quinazoline-2,4-dione | n/a | |
| 3 | Q9UGN5_2YQ | 2YQ | DB11760 | 135565082 | CHEMBL3137320 | (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one | inhibitor | |
| 4 | Q9UGN5_3AB | 3AB | n/a | 1645 | CHEMBL81977 | 3-aminobenzamide | n/a | |
| 5 | Q9UGN5_78P | 78P | DB07232 | 11960529 | CHEMBL506871 | (2R)-2-(7-carbamoyl-1H-benzimidazol-2-yl)-2-methylpyrrolidinium | n/a | IC50(nM) = 1.3 Kd(nM) = 5.8 |
| 6 | Q9UGN5_D7N | D7N | n/a | 49843531 | CHEMBL3606021 | 2-[1-(4,4-Difluorocyclohexyl)-piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide | n/a | |
| 7 | Q9UGN5_FSU | FSU | n/a | 20854918 | CHEMBL3605967 | 2-(3-methoxypropyl)-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide | n/a | |
| 8 | Q9UGN5_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 9 | Q9UGN5_I5F | I5F | n/a | 33702003 | CHEMBL5406267 | [1,2,4]triazolo[3,4-b][1,3]benzothiazol-6-ol | n/a | |
| 10 | Q9UGN5_UHB | UHB | n/a | n/a | n/a | 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide | n/a | |
| 11 | Q9UGN5_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 12 | Q9UGN5_3JD | 3JD | DB11793 | 24958200 | CHEMBL1094636 | Niraparib | inhibitor | |
| 13 | Q9UGN5_RPB | RPB | DB12332 | 9931954 | CHEMBL1173055 | Rucaparib | inhibitor |