Gene name: BACE2
Protein name: Beta-secretase 2 (EC
List of molecules and drugs that interact with protein Q9Y5Z0
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q9Y5Z0_0BK | 0BK | n/a | 156612913 | CHEMBL5082356 | N-{3-[(2S,5R)-6-amino-2-(fluoromethyl)-5-(methanesulfonyl)-5-methyl-2,3,4,5-tetrahydropyridin-2-yl]-4-fluorophenyl}-6-methoxypyrimidine-4-carboxamide | n/a | |
| 2 | Q9Y5Z0_0QQ | 0QQ | n/a | 162366968 | CHEMBL5075689 | N-[3-[(4R,5R,6R)-2-azanyl-5-fluoranyl-4,6-dimethyl-5,6-dihydro-1,3-thiazin-4-yl]-4-fluoranyl-phenyl]-2,3-dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxamide | n/a | |
| 3 | Q9Y5Z0_66F | 66F | DB12285 | 51352361 | CHEMBL3301601 | N-{3-[(5R)-3-amino-2,5-dimethyl-1,1-dioxido-5,6-dihydro-2H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl}-5-fluoropyridine-2-carboxamide | n/a | |
| 4 | Q9Y5Z0_6T9 | 6T9 | n/a | 71305034 | CHEMBL2347367 | 5-Ethoxy-pyridine-2-carboxylic acid [3-((R)-2-amino-5,5-difluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-4-yl)-4-fluoro-phenyl]-amide | n/a | |
| 5 | Q9Y5Z0_B3P | B3P | DB02676 | 125132 | CHEMBL63859 | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | n/a | |
| 6 | Q9Y5Z0_C7O | C7O | n/a | 138454796 | CHEMBL4465534 | N-[3-[(5R)-3-azanyl-5-methyl-9,9-bis(oxidanylidene)-2,9$l^{6}-dithia-4-azaspiro[5.5]undec-3-en-5-yl]-4-fluoranyl-phenyl]-5-(fluoranylmethoxy)pyrazine-2-carboxamide | n/a | |
| 7 | Q9Y5Z0_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 8 | Q9Y5Z0_DBO | DBO | n/a | 11963503 | n/a | N-{(1S,2R)-1-BENZYL-2-HYDROXY-3-[(3-METHYLBENZYL)AMINO]PROPYL}DIBENZO[B,F]OXEPINE-10-CARBOXAMIDE | n/a | |
| 9 | Q9Y5Z0_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 10 | Q9Y5Z0_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 11 | Q9Y5Z0_GX6 | GX6 | n/a | 155818878 | n/a | N-[3-[(9S)-7-azanyl-2,2-bis(fluoranyl)-9-prop-1-ynyl-6-oxa-8-azaspiro[3.5]non-7-en-9-yl]-4-fluoranyl-phenyl]-5-cyano-pyridine-2-carboxamide | n/a | |
| 12 | Q9Y5Z0_L3M | L3M | n/a | 139209087 | n/a | (3S)-3-hydroxy-N-(2-methylpropyl)-N~2~-{[(4S)-17-[(methylsulfonyl)(propyl)amino]-2-oxo-3-azatricyclo[13.3.1.1~6,10~]icosa-1(19),6(20),7,9,15,17-hexaen-4-yl]methyl}-L-norleucinamide | n/a | |
| 13 | Q9Y5Z0_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 14 | Q9Y5Z0_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 15 | Q9Y5Z0_WZV | WZV | n/a | 49819211 | n/a | 5-(2,2,2-Trifluoro-ethoxy)-pyridine-2-carboxylic acid [3-((S)-2-amino-1,4-dimethyl-6-oxo-1,4,5,6-tetrahydro-pyrimidin-4-yl)-phenyl]-amide | n/a |