Gene name: CYP46A1
Protein name: Cholesterol 24-hydroxylase (CH24H)
List of molecules and drugs that interact with protein Q9Y6A2
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q9Y6A2_04Y | 04Y | n/a | 118450420 | CHEMBL4594072 | N-cyclopropyl-1-(4-phenylpyridin-3-yl)piperidine-4-carboxamide | n/a | |
| 2 | Q9Y6A2_05D | 05D | n/a | 118450616 | CHEMBL4532699 | N,N-dimethyl-1-[4-(4-methyl-1H-pyrazol-1-yl)pyridin-3-yl]piperidine-4-carboxamide | n/a | |
| 3 | Q9Y6A2_0I1 | 0I1 | n/a | 76283989 | CHEMBL4558147 | (3-fluoroazetidin-1-yl){1-[4-(4-fluorophenyl)pyrimidin-5-yl]piperidin-4-yl}methanone | n/a | |
| 4 | Q9Y6A2_0U9 | 0U9 | n/a | 441405 | CHEMBL124881 | S-bicalutamide | n/a | |
| 5 | Q9Y6A2_198 | 198 | DB02932 | 56069 | CHEMBL63560 | R-BICALUTAMIDE | n/a | |
| 6 | Q9Y6A2_C3S | C3S | DB01990 | 65076 | CHEMBL1231592 | CHOLEST-5-EN-3-YL HYDROGEN SULFATE | n/a | |
| 7 | Q9Y6A2_CL6 | CL6 | DB00257 | 2812 | CHEMBL104 | 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE | n/a | |
| 8 | Q9Y6A2_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 9 | Q9Y6A2_FJZ | FJZ | n/a | 5450;3035905; | CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide | n/a | |
| 10 | Q9Y6A2_FVX | FVX | DB00176 | 5324346 | CHEMBL814 | Fluvoxamine | n/a | |
| 11 | Q9Y6A2_GJZ | GJZ | DB00752 | 19493 | CHEMBL1179 | (1R,2S)-2-phenylcyclopropanamine | n/a | |
| 12 | Q9Y6A2_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 13 | Q9Y6A2_HEM | HEM | DB18267 | n/a | n/a | PROTOPORPHYRIN IX CONTAINING FE | n/a | |
| 14 | Q9Y6A2_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 15 | Q9Y6A2_VOR | VOR | DB00582 | 71616 | CHEMBL638 | Voriconazole | n/a | IC50(nM) = 10000.0 |
| 16 | Q9Y6A2_X2N | X2N | DB01263 | 468595 | CHEMBL1397 | POSACONAZOLE | n/a | |
| 17 | Q9Y6A2_YBS | YBS | DB16987 | 73437845 | CHEMBL4298172 | [4-oxidanyl-4-(phenylmethyl)piperidin-1-yl]-(2-pyridin-4-ylpyridin-3-yl)methanone | inhibitor | |
| 18 | Q9Y6A2_YCG | YCG | n/a | 144059770 | CHEMBL5285548 | [5,5-dimethyl-3-(2-methylphenyl)-4~{H}-pyrazol-1-yl]-pyridin-4-yl-methanone | n/a | |
| 19 | Q9Y6A2_YCJ | YCJ | n/a | 86680843 | CHEMBL5276973 | (5-methyl-2-pyridin-4-yl-phenyl)-[4-oxidanyl-4-(phenylmethyl)piperidin-1-yl]methanone | n/a |