Gene name: STK24
Protein name: Serine/threonine-protein kinase 24
List of molecules and drugs that interact with protein Q9Y6E0
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q9Y6E0_1N1 | 1N1 | DB01254 | 3062316 | CHEMBL1421 | N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE | n/a | Kd(nM) = 10000.0 |
| 2 | Q9Y6E0_34L | 34L | n/a | 6490494 | CHEMBL235641 | (8Z)-8-(1H-imidazol-5-ylmethylidene)-6,8-dihydro-7H-[1,3]thiazolo[5,4-e]indol-7-one | n/a | |
| 3 | Q9Y6E0_34U | 34U | n/a | 10158940 | CHEMBL4303508 | 1-{2-[5-(2-methoxyethoxy)-1H-benzimidazol-1-yl]quinolin-8-yl}piperidin-4-amine | n/a | |
| 4 | Q9Y6E0_34W | 34W | DB13059 | 51346455 | CHEMBL4289017 | N-{2-[(1S,4R)-6-{[4-(cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1,2,3,4-tetrahydro-1,4-epiminonaphthalen-9-yl]-2-oxoethyl}acetamide | n/a | |
| 5 | Q9Y6E0_35R | 35R | DB05169 | 135398495 | CHEMBL495727 | 1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl}urea | n/a | |
| 6 | Q9Y6E0_3FE | 3FE | n/a | 72706840 | CHEMBL3393348 | 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile | n/a | |
| 7 | Q9Y6E0_3JA | 3JA | n/a | 72706837 | CHEMBL3393439 | 5-(1-methyl-1H-pyrazol-4-yl)-4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidine | n/a | |
| 8 | Q9Y6E0_3JB | 3JB | n/a | 91623338 | CHEMBL3393450 | 3-{4-[(2R)-2-(5-methyl-1,2,4-oxadiazol-3-yl)morpholin-4-yl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl}benzonitrile | n/a | |
| 9 | Q9Y6E0_59T | 59T | n/a | n/a | CHEMBL3770443 | 8-[(trans-5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one | n/a | |
| 10 | Q9Y6E0_627 | 627 | DB11778 | 11442891 | CHEMBL402548 | N-[(3E)-5-[(2R)-2-METHOXY-2-PHENYLACETYL]PYRROLO[3,4-C]PYRAZOL-3(5H)-YLIDENE]-4-(4-METHYLPIPERAZIN-1-YL)BENZAMIDE | n/a | |
| 11 | Q9Y6E0_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 12 | Q9Y6E0_ADP | ADP | DB16833 | 6022 | CHEMBL14830 | ADENOSINE-5'-DIPHOSPHATE | n/a | |
| 13 | Q9Y6E0_ANP | ANP | n/a | 33113 | CHEMBL1230989 | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | n/a | |
| 14 | Q9Y6E0_B49 | B49 | DB01268 | 5329102 | CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide | n/a | Kd(nM) = 63.0 |
| 15 | Q9Y6E0_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 16 | Q9Y6E0_DB8 | DB8 | DB06616 | 5328940 | CHEMBL288441 | 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile | n/a | IC50(nM) = 3.9 Kd(nM) = 380.0 |
| 17 | Q9Y6E0_DKI | DKI | DB07664 | 5330812 | CHEMBL261720 | 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE | n/a | |
| 18 | Q9Y6E0_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 19 | Q9Y6E0_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 20 | Q9Y6E0_H1N | H1N | DB04703 | n/a | n/a | N-[2-OXO-3-((E)-PHENYL{[4-(PIPERIDIN-1-YLMETHYL)PHENYL]IMINO}METHYL)-2,6-DIHYDRO-1H-INDOL-5-YL]ETHANESULFONAMIDE | n/a | |
| 21 | Q9Y6E0_H8H | H8H | DB11805 | 10302451 | CHEMBL217092 | N-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-7-[2-(4-METHYLPIPERAZIN-1-YL)ETHOXY]-5-(TETRAHYDRO-2H-PYRAN-4-YLOXY)QUINAZOLIN-4-AMINE | n/a | |
| 22 | Q9Y6E0_HG | HG | n/a | 26623 | n/a | MERCURY (II) ION | n/a | |
| 23 | Q9Y6E0_KS1 | KS1 | DB08052 | 24905142 | CHEMBL1081312 | 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | n/a | |
| 24 | Q9Y6E0_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 25 | Q9Y6E0_MN | MN | n/a | 27854 | n/a | MANGANESE (II) ION | n/a | |
| 26 | Q9Y6E0_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 27 | Q9Y6E0_PG4 | PG4 | n/a | 8200 | CHEMBL1235254 | TETRAETHYLENE GLYCOL | n/a | |
| 28 | Q9Y6E0_PGE | PGE | DB02327 | 8172 | CHEMBL1235259 | TRIETHYLENE GLYCOL | n/a | |
| 29 | Q9Y6E0_SJL | SJL | n/a | 166451135 | CHEMBL5402213 | 8-(4-azanylbutyl)-6-[2,5-bis(fluoranyl)-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one | n/a | |
| 30 | Q9Y6E0_SJX | SJX | n/a | 166451136 | n/a | 8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one | n/a | |
| 31 | Q9Y6E0_SKE | SKE | n/a | 5330790 | CHEMBL191003 | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1H-1,2,4-triazol-3-yl}amino)benzenesulfonamide | n/a | |
| 32 | Q9Y6E0_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 33 | Q9Y6E0_VY0 | VY0 | n/a | 169452785 | n/a | macrocyclic inhibitor | n/a | |
| 34 | Q9Y6E0_VYH | VYH | n/a | 169408423 | n/a | 8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-(3-morpholin-4-ylpropylamino)pyrido[2,3-d]pyrimidin-7-one | n/a | |
| 35 | Q9Y6E0_VYN | VYN | n/a | 169408422 | n/a | 8-(4-azanylbutyl)-2-[1,3-bis(oxidanyl)propan-2-ylamino]-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]pyrido[2,3-d]pyrimidin-7-one | n/a | |
| 36 | Q9Y6E0_VZ2 | VZ2 | n/a | 169408424 | n/a | 8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-[3-(2-oxidanylidenepyrrolidin-1-yl)propylamino]pyrido[2,3-d]pyrimidin-7-one | n/a | |
| 37 | Q9Y6E0_SQ8 | SQ8 | n/a | n/a | n/a | 1-[(5-azanyl-1,3-dioxan-2-yl)methyl]-3-[2-chloranyl-4-(3-fluoranylpyridin-2-yl)phenyl]-7-(methylamino)-1,6-naphthyridin-2-one | n/a | |
| 38 | Q9Y6E0_SQB | SQB | n/a | n/a | CHEMBL5169576 | 8-[(5-azanyl-1,3-dioxan-2-yl)methyl]-6-[2-chloranyl-4-(3-methoxy-6-methyl-pyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one | n/a | |
| 39 | Q9Y6E0_SQE | SQE | n/a | n/a | CHEMBL5175296 | 8-[(5-azanyl-1,3-dioxan-2-yl)methyl]-6-[4-[6-[bis(fluoranyl)methyl]pyridin-2-yl]-2-chloranyl-phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one | n/a | |
| 40 | Q9Y6E0_SQK | SQK | n/a | n/a | CHEMBL5194644 | 8-[(5-azanyl-1,3-dioxan-2-yl)methyl]-6-[2-chloranyl-4-(3-fluoranyl-6-methyl-pyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one | n/a | |
| 41 | Q9Y6E0_SQQ | SQQ | n/a | n/a | CHEMBL5180834 | 8-[(5-azanyl-1,3-dioxan-2-yl)methyl]-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-[(2-methoxyphenyl)amino]pyrido[2,3-d]pyrimidin-7-one | n/a | |
| 42 | Q9Y6E0_STU | STU | DB02010 | 44259 | CHEMBL388978 | STAUROSPORINE | n/a | |
| 43 | Q9Y6E0_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor |