Gene name: PARP3
Protein name: Protein mono-ADP-ribosyltransferase PARP3
List of molecules and drugs that interact with protein Q9Y6F1
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q9Y6F1_1DC | 1DC | n/a | 25943376;135566840; | CHEMBL5027667 | 3-(4-oxo-3,4-dihydroquinazolin-2-yl)-N-[(1S)-1-(pyridin-4-yl)ethyl]propanamide | n/a | |
| 2 | Q9Y6F1_1V9 | 1V9 | n/a | 72771090;135566841; | CHEMBL3092544 | 3-(4-oxo-3,4-dihydroquinazolin-2-yl)-N-[(1S)-1-phenylpropyl]propanamide | n/a | |
| 3 | Q9Y6F1_1VA | 1VA | n/a | 72771093;135566842; | CHEMBL3092553 | N-[(2S)-1-hydroxy-3-phenylpropan-2-yl]-3-(4-oxo-3,4-dihydroquinazolin-2-yl)propanamide | n/a | |
| 4 | Q9Y6F1_1VB | 1VB | n/a | 25620222;135566843; | n/a | 3-(4-oxo-3,4-dihydroquinazolin-2-yl)-N-[(1S)-1-(4-sulfamoylphenyl)ethyl]propanamide | n/a | |
| 5 | Q9Y6F1_1VC | 1VC | n/a | 9269589;135566846; | CHEMBL3092523 | methyl N-[3-(4-oxo-3,4-dihydroquinazolin-2-yl)propanoyl]-L-phenylalaninate | n/a | |
| 6 | Q9Y6F1_1VD | 1VD | n/a | 9115134;135566844; | n/a | N-{(1S)-1-[4-(1H-imidazol-1-yl)phenyl]ethyl}-3-(4-oxo-3,4-dihydroquinazolin-2-yl)propanamide | n/a | |
| 7 | Q9Y6F1_5ME | 5ME | n/a | 9107457;135566762; | CHEMBL3092538 | 3-(4-oxo-3,4-dihydroquinazolin-2-yl)-N-[(1R)-1-(pyridin-2-yl)ethyl]propanamide | n/a | |
| 8 | Q9Y6F1_8ME | 8ME | n/a | 9107452;135566761; | CHEMBL3092539 | 3-(4-oxo-3,4-dihydroquinazolin-2-yl)-N-[(1S)-1-(pyridin-2-yl)ethyl]propanamide | n/a | |
| 9 | Q9Y6F1_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 10 | Q9Y6F1_DRL | DRL | DB07677 | 10219702;135522417; | CHEMBL483348 | 2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one | n/a | Kd(nM) = 2000.0 |
| 11 | Q9Y6F1_GAB | GAB | DB02054 | 7419 | CHEMBL307782 | 3-AMINOBENZOIC ACID | n/a | Kd(nM) = 2000.0 |
| 12 | Q9Y6F1_KU8 | KU8 | DB08058 | 11291932 | CHEMBL380648 | 4-[3-(1,4-diazepan-1-ylcarbonyl)-4-fluorobenzyl]phthalazin-1(2H)-one | n/a | Kd(nM) = 70.0 |
| 13 | Q9Y6F1_M00 | M00 | n/a | 72771094;135566845; | CHEMBL3092521 | N-[(2S)-1-hydroxybutan-2-yl]-3-(4-oxo-3,4-dihydroquinazolin-2-yl)propanamide | n/a | |
| 14 | Q9Y6F1_M95 | M95 | n/a | 72792620;136224185; | CHEMBL3092519 | (2E)-N-[(2S)-1-hydroxy-3-phenylpropan-2-yl]-3-(4-oxo-1,4-dihydroquinazolin-2-yl)prop-2-enamide | n/a | |
| 15 | Q9Y6F1_MEJ | MEJ | n/a | 71571526;135566764; | CHEMBL3092537 | 3-(4-oxo-3,4-dihydroquinazolin-2-yl)-N-[(1S)-1-phenylethyl]propanamide | n/a | |
| 16 | Q9Y6F1_P34 | P34 | DB08348 | 4858;5289097; | CHEMBL372303 | N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE | n/a | IC50(nM) = 1430.0 Kd(nM) = 700.0 |
| 17 | Q9Y6F1_09L | 09L | DB09074 | 23725625 | CHEMBL521686 | Olaparib | inhibitor | |
| 18 | Q9Y6F1_RPB | RPB | DB12332 | 9931954 | CHEMBL1173055 | Rucaparib | inhibitor |