Gene name: Keap1
Protein name: Kelch-like ECH-associated protein
List of molecules and drugs that interact with protein Q9Z2X8
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q9Z2X8_0PL | 0PL | n/a | 118170891 | CHEMBL3818085 | (3S)-3-{4-Chloro-3-[(N-methylbenzenesulfonamido) methyl]phenyl}-3-(1-methyl-1H-1,2,3-benzotriazol-5-yl)propanoic acid | n/a | |
| 2 | Q9Z2X8_51M | 51M | n/a | 91971266 | CHEMBL3899754 | (3S)-1-(4-{[(2,3,5,6-tetramethylphenyl)sulfonyl]amino}naphthalen-1-yl)pyrrolidine-3-carboxylic acid | n/a | |
| 3 | Q9Z2X8_5QZ | 5QZ | n/a | 157010570 | CHEMBL5169432 | 5-cyclopropyl-1-[3-[3-(dimethylcarbamoyl)phenyl]phenyl]pyrazole-4-carboxylic acid | n/a | |
| 4 | Q9Z2X8_5RB | 5RB | n/a | 126754534 | CHEMBL5194960 | 5-[(1~{R},2~{R})-2-(1-methyl-1,2,3-triazol-4-yl)cyclopropyl]-1-[3-[3-[(2~{R})-2-propylpiperidin-1-yl]carbonylphenyl]phenyl]pyrazole-4-carboxylic acid | n/a | |
| 5 | Q9Z2X8_5RQ | 5RQ | n/a | 129024631 | CHEMBL5199314 | 1-[3-[(1~{R},3~{S})-3-[(2~{R})-2-butylpyrrolidin-1-yl]carbonylcyclohexyl]phenyl]-5-cyclopropyl-pyrazole-4-carboxylic acid | n/a | |
| 6 | Q9Z2X8_5UI | 5UI | n/a | 126754445 | CHEMBL5172398 | 1-[6-(3-propan-2-yloxyphenyl)pyridin-2-yl]-5-(trifluoromethyl)pyrazole-4-carboxylic acid | n/a | |
| 7 | Q9Z2X8_5UZ | 5UZ | n/a | 126754491 | CHEMBL5177628 | 5-cyclopropyl-1-[3-[2-fluoranyl-3-[(2~{R})-2-propylpiperidin-1-yl]carbonyl-phenyl]phenyl]pyrazole-4-carboxylic acid | n/a | |
| 8 | Q9Z2X8_5VX | 5VX | n/a | 157010569 | CHEMBL5195110 | 1-[6-[3-(dimethylcarbamoyl)phenyl]pyridin-2-yl]-5-(trifluoromethyl)pyrazole-4-carboxylic acid | n/a | |
| 9 | Q9Z2X8_5X9 | 5X9 | n/a | 157010571 | n/a | 1-[3-[3-(dimethylcarbamoyl)phenyl]phenyl]-5-[(1~{R},2~{R})-2-(1-methyl-1,2,3-triazol-4-yl)cyclopropyl]pyrazole-4-carboxylic acid | n/a | |
| 10 | Q9Z2X8_75K | 75K | n/a | 118987023 | n/a | 2,6-DIMETHYL-4H-PYRANO[3,4-D][1,3]OXAZOL-4-ONE | n/a | |
| 11 | Q9Z2X8_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 12 | Q9Z2X8_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 13 | Q9Z2X8_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 14 | Q9Z2X8_DHC | DHC | DB01880 | 689043 | CHEMBL145 | CAFFEIC ACID | n/a | |
| 15 | Q9Z2X8_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 16 | Q9Z2X8_FB2 | FB2 | n/a | 7370;14928400; | CHEMBL27601 | benzenesulfonamide | n/a | |
| 17 | Q9Z2X8_FMT | FMT | DB01942 | 284;18971002; | CHEMBL116736 | FORMIC ACID | n/a | |
| 18 | Q9Z2X8_FUM | FUM | DB01677 | 444972;21883788; | CHEMBL503160 | FUMARIC ACID | n/a | |
| 19 | Q9Z2X8_IZS | IZS | n/a | 168719757 | n/a | ethyl 2-[(4,6-diethylpyrimidin-2-yl)-methyl-amino]ethanoate | n/a | |
| 20 | Q9Z2X8_J6H | J6H | n/a | 137797042 | n/a | (3~{S})-3-(4-chlorophenyl)-3-(2-oxidanylidene-1~{H}-pyridin-4-yl)propanoic acid | n/a | |
| 21 | Q9Z2X8_J6K | J6K | n/a | 137797045 | n/a | (3~{S})-3-(7-methoxy-1-methyl-benzotriazol-5-yl)-3-[4-methyl-3-[[methyl(phenylsulfonyl)amino]methyl]phenyl]propanoic acid | n/a | |
| 22 | Q9Z2X8_J6N | J6N | n/a | 137797043 | CHEMBL4572418 | (3~{R})-3-(4-chlorophenyl)-3-(1-methylbenzotriazol-5-yl)propanoic acid | n/a | |
| 23 | Q9Z2X8_J6Q | J6Q | n/a | 137797044 | n/a | (3~{S})-3-(4-chloranyl-3-methyl-phenyl)-3-(1-methylbenzotriazol-5-yl)propanoic acid | n/a | |
| 24 | Q9Z2X8_J8H | J8H | n/a | 137797046 | n/a | (3~{S})-3-[3-[[1,1-bis(oxidanylidene)-3,4-dihydro-5,1$l^{6},2-benzoxathiazepin-2-yl]methyl]-4-methyl-phenyl]-3-(7-methoxy-1-methyl-benzotriazol-5-yl)propanoic acid | n/a | |
| 25 | Q9Z2X8_K67 | K67 | n/a | 119057445 | CHEMBL3948237 | N,N'-[2-(2-oxopropyl)naphthalene-1,4-diyl]bis(4-ethoxybenzenesulfonamide) | n/a | |
| 26 | Q9Z2X8_L5F | L5F | n/a | 164513568 | n/a | 2-[(1S,2R,8S)-2,4,32-trimethyl-28,28-bis(oxidanylidene)-19,22,27-trioxa-28$l^{6}-thia-1,14,15,16-tetrazahexacyclo[21.5.3.1^{3,7}.1^{9,13}.0^{12,16}.0^{26,30}]tritriaconta-3(33),4,6,9(32),10,12,14,23,25,30-decaen-8-yl]ethanoic acid | n/a | |
| 27 | Q9Z2X8_L6I | L6I | n/a | 118170767 | CHEMBL3819587 | (3S)-3-(7-methoxy-1-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(4-methyl-3-(((R)-4-methyl-1,1-dioxido-3,4-dihydro-2H-benzo[b][1,4,5]oxathiazepin-2-yl)methyl)phenyl)propanoic acid | n/a | |
| 28 | Q9Z2X8_NF3 | NF3 | n/a | 5354457 | n/a | (~{Z})-4-ethoxy-4-oxidanylidene-but-2-enoic acid | n/a | |
| 29 | Q9Z2X8_PGE | PGE | DB02327 | 8172 | CHEMBL1235259 | TRIETHYLENE GLYCOL | n/a | |
| 30 | Q9Z2X8_QGZ | QGZ | n/a | 155884472 | CHEMBL4865680 | 5-cyclopropyl-1-[3-(phenylsulfonylamino)phenyl]pyrazole-4-carboxylic acid | n/a | |
| 31 | Q9Z2X8_QH2 | QH2 | n/a | 155884473 | CHEMBL4847104 | 1-[3-[2-hydroxy-2-oxoethyl(phenylsulfonyl)amino]phenyl]-5-[(1~{S},2~{S})-2-phenylcyclopropyl]pyrazole-4-carboxylic acid | n/a | |
| 32 | Q9Z2X8_QH5 | QH5 | n/a | 155884474 | CHEMBL4848597 | ~{N}-[3-[5-cyclopropyl-4-(2~{H}-1,2,3,4-tetrazol-5-yl)pyrazol-1-yl]phenyl]benzenesulfonamide | n/a | |
| 33 | Q9Z2X8_QH8 | QH8 | n/a | 155884475 | CHEMBL4872361 | 1-[3-[(4-butylphenyl)sulfonyl-(2-hydroxy-2-oxoethyl)amino]phenyl]-5-cyclopropyl-pyrazole-4-carboxylic acid | n/a | |
| 34 | Q9Z2X8_QHB | QHB | n/a | 590941 | CHEMBL4879253 | 7-methoxy-1~{H}-benzotriazole | n/a | |
| 35 | Q9Z2X8_QHH | QHH | n/a | 129024632 | n/a | 1-[3-[(1~{R},3~{S})-3-[(2~{S})-2-butylpyrrolidin-1-yl]carbonylcyclohexyl]phenyl]-5-cyclopropyl-pyrazole-4-carboxylic acid | n/a | |
| 36 | Q9Z2X8_QHK | QHK | n/a | 155884476 | CHEMBL4849150 | 5-cyclopropyl-1-[3-[2-hydroxy-2-oxoethyl(phenylsulfonyl)amino]phenyl]pyrazole-4-carboxylic acid | n/a | |
| 37 | Q9Z2X8_QHN | QHN | n/a | 22267908 | CHEMBL4867889 | 5-cyclopropyl-1-phenyl-pyrazole-4-carboxylic acid | n/a | |
| 38 | Q9Z2X8_QHQ | QHQ | n/a | 155884477 | CHEMBL4847787 | 5-cyclopropyl-1-[3-[2-hydroxy-2-oxoethyl-(3-methoxyphenyl)sulfonyl-amino]phenyl]pyrazole-4-carboxylic acid | n/a | |
| 39 | Q9Z2X8_QHT | QHT | n/a | 155884478 | CHEMBL4860409 | 5-cyclopropyl-1-[3-[(2,3,5,6-tetramethylphenyl)sulfonylamino]phenyl]pyrazole-4-carboxylic acid | n/a | |
| 40 | Q9Z2X8_QHW | QHW | n/a | 155884479 | CHEMBL4868608 | 5-cyclopropyl-1-[3-[2-hydroxy-2-oxoethyl-(2,3,5,6-tetramethylphenyl)sulfonyl-amino]phenyl]pyrazole-4-carboxylic acid | n/a | |
| 41 | Q9Z2X8_QHZ | QHZ | n/a | 155884480 | CHEMBL4860934 | 1-[3-[2-hydroxy-2-oxoethyl-(3-methoxyphenyl)sulfonyl-amino]phenyl]-5-[(1~{S},2~{S})-2-phenylcyclopropyl]pyrazole-4-carboxylic acid | n/a | |
| 42 | Q9Z2X8_QJ5 | QJ5 | n/a | 155884481 | CHEMBL4872029 | 5-cyclopropyl-1-[3-[(4-propylphenyl)sulfonylamino]phenyl]pyrazole-4-carboxylic acid | n/a | |
| 43 | Q9Z2X8_S0W | S0W | n/a | 123137 | CHEMBL3819037 | 3-(4-CHLOROPHENYL)PROPANOIC ACID | n/a | |
| 44 | Q9Z2X8_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 45 | Q9Z2X8_TRS | TRS | DB03754 | 3777159;88088752;152743085; | n/a | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | n/a | |
| 46 | Q9Z2X8_VBK | VBK | n/a | 42556025 | n/a | [(4S)-6,7-dihydro-4H-thieno[3,2-c]pyran-4-yl]methanamine | n/a | |
| 47 | Q9Z2X8_VBQ | VBQ | n/a | 165416264 | CHEMBL5218656 | 2-[(9-oxidanylidenefluoren-4-yl)carbonylamino]ethanoic acid | n/a | |
| 48 | Q9Z2X8_VBT | VBT | n/a | 2733659 | CHEMBL5220253 | 2,6-bis(chloranyl)-5-fluoranyl-pyridine-3-carboxylic acid | n/a | |
| 49 | Q9Z2X8_VBW | VBW | n/a | 85184 | CHEMBL5220089 | 6-fluoranyl-2-methyl-quinolin-4-ol | n/a | |
| 50 | Q9Z2X8_VCB | VCB | n/a | 7553306 | n/a | (2~{R})-2-[(9-oxidanylidenefluoren-4-yl)carbonylamino]-2-phenyl-ethanoic acid | n/a | |
| 51 | Q9Z2X8_VCN | VCN | n/a | 2801781 | CHEMBL1486504 | ~{N},~{N}-diethyl-9-oxidanylidene-fluorene-4-carboxamide | n/a | |
| 52 | Q9Z2X8_VCQ | VCQ | n/a | 948619 | n/a | (2~{S})-2-cyclopentyl-2-oxidanyl-2-phenyl-ethanoic acid | n/a | |
| 53 | Q9Z2X8_VCT | VCT | n/a | 2801780 | CHEMBL5219152 | ~{N},~{N}-dimethyl-9-oxidanylidene-fluorene-4-carboxamide | n/a | |
| 54 | Q9Z2X8_XMS | XMS | n/a | 118987021 | CHEMBL4436743 | (3S)-3-(4-chlorophenyl)-3-(1-methylbenzotriazol-5-yl)propanoic acid | n/a | |
| 55 | Q9Z2X8_XYY | XYY | n/a | 118987022 | n/a | (3s)-{4-Chloro-3-[(N-methylmethanesulfonamido) methyl]phenyl}-3-(1-methyl-1H-1,2,3-benzotriazol-5-yl) propanoic acid | n/a |