DrugDomain logoDrugDomain

3-(5-{[4-(AMINOMETHYL)PIPERIDIN-1-YL]METHYL}-1H-INDOL-2-YL)QUINOLIN-2(1H)-ONE

O14757 — Serine/threonine-protein kinase Chk1

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Attributes

UniProt ID
O14757
Protein Name
Serine/threonine-protein kinase Chk1
Ligand Name
3-(5-{[4-(AMINOMETHYL)PIPERIDIN-1-YL]METHYL}-1H-INDOL-2-YL)QUINOLIN-2(1H)-ONE
DrugBank ID
DB07025
PDB Ligand Accession
373
ChEMBL ID
CHEMBL221735
PubChem ID
10156987
InChIKey
KBIHHEGEALBUMT-UHFFFAOYSA-N
SMILES
c1ccc2c(c1)C=C(C(=O)N2)c3cc4cc(ccc4[nH]3)CN5CCC(CC5)CN
Drug Action
n/a
Affinity Metrics
ic50:140 nM