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1-(5-CHLORO-2,4-DIMETHOXYPHENYL)-3-(5-CYANOPYRAZIN-2-YL)UREA

O14757 — Serine/threonine-protein kinase Chk1

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Attributes

UniProt ID
O14757
Protein Name
Serine/threonine-protein kinase Chk1
Ligand Name
1-(5-CHLORO-2,4-DIMETHOXYPHENYL)-3-(5-CYANOPYRAZIN-2-YL)UREA
DrugBank ID
DB07314
PDB Ligand Accession
A42
ChEMBL ID
CHEMBL207994
PubChem ID
16122643
InChIKey
URQYPXQXSVUVRG-UHFFFAOYSA-N
SMILES
COc1cc(c(cc1NC(=O)Nc2cnc(cn2)C#N)Cl)OC
Drug Action
n/a
Affinity Metrics
ki:10 nM
ic50:7 nM