1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}-3-[3-(trifluoromethyl)phenyl]urea

O14965 — Aurora kinase A

Attributes

UniProt ID

Protein Name

Aurora kinase A

Ligand Name

1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}-3-[3-(trifluoromethyl)phenyl]urea

DrugBank ID

PDB Ligand Accession

ChEMBL ID

PubChem ID

InChIKey

JJHXPDTVQKWKHA-UHFFFAOYSA-N

SMILES

c1cc(cc(c1)NC(=O)Nc2ncc(s2)CCNc3c4c(ccs4)ncn3)C(F)(F)F

Drug Action

n/a

Affinity Metrics

ic50:22 nM