DrugDomain logoDrugDomain

3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide

O43353 — Receptor-interacting serine/threonine-protein kinase 2

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Attributes

UniProt ID
O43353
Protein Name
Receptor-interacting serine/threonine-protein kinase 2
Ligand Name
3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide
DrugBank ID
DB08901
PDB Ligand Accession
0LI
ChEMBL ID
CHEMBL1171837
PubChem ID
24826799
InChIKey
PHXJVRSECIGDHY-UHFFFAOYSA-N
SMILES
Cc1ccc(cc1C#Cc2cnc3n2nccc3)C(=O)Nc4ccc(c(c4)C(F)(F)F)CN5CCN(CC5)C
Drug Action
no_target_action
Affinity Metrics
ic50:1 nM