[(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone

O43613 — Orexin/Hypocretin receptor type 1

Attributes

UniProt ID

Protein Name

Orexin/Hypocretin receptor type 1

Ligand Name

[(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone

DrugBank ID

PDB Ligand Accession

ChEMBL ID

PubChem ID

InChIKey

JYTNQNCOQXFQPK-MRXNPFEDSA-N

SMILES

Cc1ccc(c(c1)C(=O)N2CCN(CCC2C)c3nc4cc(ccc4o3)Cl)n5nccn5

Drug Action

antagonist

Affinity Metrics

ki:0.398107 nM

ic50:50 nM