6-BENZO[1,3]DIOXOL-5-YL-2-METHYL-2,3,6,7,12,12A-HEXAHYDRO-PYRAZINO[1',2':1,6]PYRIDO[3,4-B]INDOLE-1,4-DIONE

O76074 — cGMP-specific 3',5'-cyclic phosphodiesterase

Attributes

UniProt ID

Protein Name

cGMP-specific 3',5'-cyclic phosphodiesterase

Ligand Name

6-BENZO[1,3]DIOXOL-5-YL-2-METHYL-2,3,6,7,12,12A-HEXAHYDRO-PYRAZINO[1',2':1,6]PYRIDO[3,4-B]INDOLE-1,4-DIONE

DrugBank ID

PDB Ligand Accession

ChEMBL ID

PubChem ID

InChIKey

WOXKDUGGOYFFRN-IIBYNOLFSA-N

SMILES

CN1CC(=O)N2C(C1=O)Cc3c4ccccc4[nH]c3C2c5ccc6c(c5)OCO6

Drug Action

inhibitor

Affinity Metrics

ki:5.2 nM

ic50:1.2 nM

ec50:5810 nM