DrugDomain logoDrugDomain

4-[(3-chloranyl-4-methoxy-phenyl)methylamino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-(pyrimidin-2-ylmethyl)pyrimid ine-5-carboxamide

O76074 — cGMP-specific 3',5'-cyclic phosphodiesterase

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Attributes

UniProt ID
O76074
Protein Name
cGMP-specific 3',5'-cyclic phosphodiesterase
Ligand Name
4-[(3-chloranyl-4-methoxy-phenyl)methylamino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-(pyrimidin-2-ylmethyl)pyrimid ine-5-carboxamide
DrugBank ID
DB06237
PDB Ligand Accession
E6L
ChEMBL ID
CHEMBL1963681
PubChem ID
9869929
InChIKey
WEAJZXNPAWBCOA-INIZCTEOSA-N
SMILES
COc1ccc(cc1Cl)CNc2c(cnc(n2)N3CCCC3CO)C(=O)NCc4ncccn4
Drug Action
inhibitor
Affinity Metrics
ki:5 nM
ic50:5200 nM