5-chloro-N~4~-[2-(dimethylphosphoryl)phenyl]-N~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine

P00519 — Tyrosine-protein kinase ABL1

Attributes

UniProt ID

Protein Name

Tyrosine-protein kinase ABL1

Ligand Name

5-chloro-N~4~-[2-(dimethylphosphoryl)phenyl]-N~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine

DrugBank ID

PDB Ligand Accession

ChEMBL ID

PubChem ID

InChIKey

AILRADAXUVEEIR-UHFFFAOYSA-N

SMILES

CN1CCN(CC1)C2CCN(CC2)c3ccc(c(c3)OC)Nc4ncc(c(n4)Nc5ccccc5P(=O)(C)C)Cl

Drug Action

inhibitor

Affinity Metrics