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[6,7-BIS(2-METHOXY-ETHOXY)QUINAZOLINE-4-YL]-(3-ETHYNYLPHENYL)AMINE

P00533 — Epidermal growth factor receptor

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Attributes

UniProt ID
P00533
Protein Name
Epidermal growth factor receptor
Ligand Name
[6,7-BIS(2-METHOXY-ETHOXY)QUINAZOLINE-4-YL]-(3-ETHYNYLPHENYL)AMINE
DrugBank ID
DB00530
PDB Ligand Accession
AQ4
ChEMBL ID
CHEMBL553
PubChem ID
176870
InChIKey
AAKJLRGGTJKAMG-UHFFFAOYSA-N
SMILES
COCCOc1cc2c(cc1OCCOC)ncnc2Nc3cccc(c3)C#C
Drug Action
antagonist
Affinity Metrics
ki:0.1 nM
ic50:0.029 nM
kd:0.35 nM