DrugDomain logoDrugDomain

N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE

P00533 — Epidermal growth factor receptor

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Attributes

UniProt ID
P00533
Protein Name
Epidermal growth factor receptor
Ligand Name
N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE
DrugBank ID
DB01259
PDB Ligand Accession
FMM
ChEMBL ID
CHEMBL554
PubChem ID
208908
InChIKey
BCFGMOOMADDAQU-UHFFFAOYSA-N
SMILES
CS(=O)(=O)CCNCc1ccc(o1)c2ccc3c(c2)c(ncn3)Nc4ccc(c(c4)Cl)OCc5cccc(c5)F
Drug Action
antagonist
Affinity Metrics
ki:3 nM
ic50:0.06 nM
kd:0.92 nM