DrugDomain logoDrugDomain

Gefitinib

P00533 — Epidermal growth factor receptor

← Back

Attributes

UniProt ID
P00533
Protein Name
Epidermal growth factor receptor
Ligand Name
Gefitinib
DrugBank ID
DB00317
PDB Ligand Accession
IRE
ChEMBL ID
CHEMBL939
PubChem ID
123631
InChIKey
XGALLCVXEZPNRQ-UHFFFAOYSA-N
SMILES
COc1cc2c(cc1OCCCN3CCOCC3)c(ncn2)Nc4ccc(c(c4)Cl)F
Drug Action
antagonist
Affinity Metrics
ki:0.4 nM
ic50:0.1 nM
kd:0.52 nM
ec50:2162 nM