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(2R,4R)-N~1~-(4-CHLOROPHENYL)-N~2~-[2-FLUORO-4-(2-OXOPYRIDIN-1(2H)-YL)PHENYL]-4-METHOXYPYRROLIDINE-1,2-DICARBOXAMIDE

P00742 — Coagulation factor X

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Attributes

UniProt ID
P00742
Protein Name
Coagulation factor X
Ligand Name
(2R,4R)-N~1~-(4-CHLOROPHENYL)-N~2~-[2-FLUORO-4-(2-OXOPYRIDIN-1(2H)-YL)PHENYL]-4-METHOXYPYRROLIDINE-1,2-DICARBOXAMIDE
DrugBank ID
DB06920
PDB Ligand Accession
230
ChEMBL ID
CHEMBL476186
PubChem ID
11634458
InChIKey
QQBKAVAGLMGMHI-WIYYLYMNSA-N
SMILES
COC1CC(N(C1)C(=O)Nc2ccc(cc2)Cl)C(=O)Nc3ccc(cc3F)N4C=CC=CC4=O
Drug Action
inhibitor
Affinity Metrics
ic50:0.32 nM