6-(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)-4-(3-METHOXYPROPYL)-2,2-DIMETHYL-2H-1,4-BENZOXAZIN-3(4H)-ONE

P00797 — Renin

Attributes

UniProt ID

Protein Name

Renin

Ligand Name

6-(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)-4-(3-METHOXYPROPYL)-2,2-DIMETHYL-2H-1,4-BENZOXAZIN-3(4H)-ONE

DrugBank ID

PDB Ligand Accession

ChEMBL ID

PubChem ID

InChIKey

WPAPODFGOZXFLG-UHFFFAOYSA-N

SMILES

CCc1c(c(nc(n1)N)N)c2ccc3c(c2)N(C(=O)C(O3)(C)C)CCCOC

Drug Action

n/a

Affinity Metrics

ic50:90 nM