DrugDomain logoDrugDomain

N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE

P04626 — Receptor tyrosine-protein kinase erbB-2

← Back

Attributes

UniProt ID
P04626
Protein Name
Receptor tyrosine-protein kinase erbB-2
Ligand Name
N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE
DrugBank ID
DB01259
PDB Ligand Accession
FMM
ChEMBL ID
CHEMBL554
PubChem ID
208908
InChIKey
BCFGMOOMADDAQU-UHFFFAOYSA-N
SMILES
CS(=O)(=O)CCNCc1ccc(o1)c2ccc3c(c2)c(ncn3)Nc4ccc(c(c4)Cl)OCc5cccc(c5)F
Drug Action
antagonist
Affinity Metrics
ic50:2.7 nM
kd:7 nM