DrugDomain logoDrugDomain

(6alpha,11alpha,14beta,16alpha,17alpha)-6,9-difluoro-17-{[(fluoromethyl)sulfanyl]carbonyl}-11-hydroxy-16-methyl-3-oxoan drosta-1,4-dien-17-yl furan-2-carboxylate

P06401 — Progesterone receptor

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Attributes

UniProt ID
P06401
Protein Name
Progesterone receptor
Ligand Name
(6alpha,11alpha,14beta,16alpha,17alpha)-6,9-difluoro-17-{[(fluoromethyl)sulfanyl]carbonyl}-11-hydroxy-16-methyl-3-oxoan drosta-1,4-dien-17-yl furan-2-carboxylate
DrugBank ID
DB08906
PDB Ligand Accession
GW6
ChEMBL ID
CHEMBL1676
PubChem ID
9854489
InChIKey
XTULMSXFIHGYFS-VLSRWLAYSA-N
SMILES
CC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)SCF)OC(=O)c5ccco5)C)O)F)C)F
Drug Action
agonist
Affinity Metrics
ic50:21 nM