DrugDomain logoDrugDomain

1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine-3-carboxamide

P08581 — Hepatocyte growth factor receptor

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Attributes

UniProt ID
P08581
Protein Name
Hepatocyte growth factor receptor
Ligand Name
1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine-3-carboxamide
DrugBank ID
DB06896
PDB Ligand Accession
1FN
ChEMBL ID
CHEMBL509101
PubChem ID
21081761
InChIKey
OBSFXHDOLBYWRJ-UHFFFAOYSA-N
SMILES
c1cc(ccc1N2C=CC=C(C2=O)C(=O)Nc3ccc(c(c3)F)Oc4ccnc5c4cc[nH]5)F
Drug Action
n/a
Affinity Metrics
ic50:1.8 nM