Yohimbine

P08913 — Alpha-2A adrenergic receptor

Attributes

UniProt ID

Protein Name

Alpha-2A adrenergic receptor

Ligand Name

Yohimbine

DrugBank ID

PDB Ligand Accession

n/a

ChEMBL ID

n/a

PubChem ID

n/a

InChIKey

n/a

SMILES

[H][C@@]12CC[C@H](O)[C@H](C(=O)OC)[C@@]1([H])C[C@]1([H])N(CCC3=C1NC1=CC=CC=C31)C2

Drug Action

antagonist

Affinity Metrics

ki:0.32 nM

ic50:3.67 nM

kd:2300 nM

ec50:8.5 nM