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(10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile

P08922 — Proto-oncogene tyrosine-protein kinase ROS

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Attributes

UniProt ID
P08922
Protein Name
Proto-oncogene tyrosine-protein kinase ROS
Ligand Name
(10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile
DrugBank ID
DB12130
PDB Ligand Accession
5P8
ChEMBL ID
CHEMBL3286830
PubChem ID
71731823
InChIKey
IIXWYSCJSQVBQM-LLVKDONJSA-N
SMILES
CC1c2cc(ccc2C(=O)N(Cc3c(c(n(n3)C)C#N)-c4cc(c(nc4)N)O1)C)F
Drug Action
inhibitor
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