DrugDomain logoDrugDomain

[6-(4-CHLOROPHENYL)-2,2-DIMETHYL-7-PHENYL-2,3-DIHYDRO-1H-PYRROLIZIN-5-YL]ACETIC ACID

P09917 — Polyunsaturated fatty acid 5-lipoxygenase

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Attributes

UniProt ID
P09917
Protein Name
Polyunsaturated fatty acid 5-lipoxygenase
Ligand Name
[6-(4-CHLOROPHENYL)-2,2-DIMETHYL-7-PHENYL-2,3-DIHYDRO-1H-PYRROLIZIN-5-YL]ACETIC ACID
DrugBank ID
DB04725
PDB Ligand Accession
LCF
ChEMBL ID
CHEMBL300982
PubChem ID
133021
InChIKey
UAWXGRJVZSAUSZ-UHFFFAOYSA-N
SMILES
CC1(Cc2c(c(c(n2C1)CC(=O)O)c3ccc(cc3)Cl)c4ccccc4)C
Drug Action
inhibitor
Affinity Metrics
ic50:180 nM