DrugDomain logoDrugDomain

4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE

P10721 — Mast/stem cell growth factor receptor Kit

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Attributes

UniProt ID
P10721
Protein Name
Mast/stem cell growth factor receptor Kit
Ligand Name
4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE
DrugBank ID
DB00619
PDB Ligand Accession
STI
ChEMBL ID
CHEMBL941
PubChem ID
5291
InChIKey
KTUFNOKKBVMGRW-UHFFFAOYSA-N
SMILES
Cc1ccc(cc1Nc2nccc(n2)c3cccnc3)NC(=O)c4ccc(cc4)CN5CCN(CC5)C
Drug Action
antagonist
Affinity Metrics
ki:14 nM
ic50:16 nM
kd:3 nM
ec50:100 nM