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{3,5-DICHLORO-4-[4-HYDROXY-3-(PROPAN-2-YL)PHENOXY]PHENYL}ACETIC ACID

P10827 — Thyroid hormone receptor alpha

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Attributes

UniProt ID
P10827
Protein Name
Thyroid hormone receptor alpha
Ligand Name
{3,5-DICHLORO-4-[4-HYDROXY-3-(PROPAN-2-YL)PHENOXY]PHENYL}ACETIC ACID
DrugBank ID
DB03176
PDB Ligand Accession
IH5
ChEMBL ID
CHEMBL41036
PubChem ID
9863447
InChIKey
OZYQIQVPUZANTM-UHFFFAOYSA-N
SMILES
CC(C)c1cc(ccc1O)Oc2c(cc(cc2Cl)CC(=O)O)Cl
Drug Action
n/a
Affinity Metrics
ki:7.18 nM
ic50:25 nM
ec50:1.7 nM