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3,5,3'TRIIODOTHYRONINE

P10827 — Thyroid hormone receptor alpha

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Attributes

UniProt ID
P10827
Protein Name
Thyroid hormone receptor alpha
Ligand Name
3,5,3'TRIIODOTHYRONINE
DrugBank ID
DB00279
PDB Ligand Accession
T3
ChEMBL ID
CHEMBL1544
PubChem ID
5920; 7048703
InChIKey
AUYYCJSJGJYCDS-LBPRGKRZSA-N
SMILES
c1cc(c(cc1Oc2c(cc(cc2I)CC(C(=O)O)N)I)I)O
Drug Action
agonist
Affinity Metrics
ki:0.22 nM
ic50:0.24 nM
kd:0.058 nM
ec50:0.41 nM