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1-(3-{6-[(CYCLOPROPYLMETHYL)AMINO]IMIDAZO[1,2-B]PYRIDAZIN-3-YL}PHENYL)ETHANONE

P11309 — Serine/threonine-protein kinase pim-1

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Attributes

UniProt ID
P11309
Protein Name
Serine/threonine-protein kinase pim-1
Ligand Name
1-(3-{6-[(CYCLOPROPYLMETHYL)AMINO]IMIDAZO[1,2-B]PYRIDAZIN-3-YL}PHENYL)ETHANONE
DrugBank ID
DB04715
PDB Ligand Accession
IYZ
ChEMBL ID
CHEMBL200528
PubChem ID
5459373
InChIKey
IVUBNTNWKIPCPS-UHFFFAOYSA-N
SMILES
CC(=O)c1cccc(c1)c2cnc3n2nc(cc3)NCC4CC4
Drug Action
n/a
Affinity Metrics
ic50:12 nM
kd:25 nM