DrugDomain logoDrugDomain

(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-(thiophen-2-ylmethylidene)-beta-D-glucopyranoside

P11388 — DNA topoisomerase 2-alpha

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Attributes

UniProt ID
P11388
Protein Name
DNA topoisomerase 2-alpha
Ligand Name
(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-(thiophen-2-ylmethylidene)-beta-D-glucopyranoside
DrugBank ID
DB00444
PDB Ligand Accession
9TP
ChEMBL ID
CHEMBL452231
PubChem ID
452548
InChIKey
NRUKOCRGYNPUPR-QBPJDGROSA-N
SMILES
COc1cc(cc(c1O)OC)C2c3cc4c(cc3C(C5C2C(=O)OC5)OC6C(C(C7C(O6)COC(O7)c8cccs8)O)O)OCO4
Drug Action
inhibitor
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