7-CHLORO-1-METHYL-5-PHENYL-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE
P14867 — Gamma-aminobutyric acid receptor subunit alpha-1 receptor subunit alpha-1
Attributes
UniProt ID
Protein Name
Gamma-aminobutyric acid receptor subunit alpha-1 receptor subunit alpha-1
Ligand Name
7-CHLORO-1-METHYL-5-PHENYL-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE
DrugBank ID
PDB Ligand Accession
ChEMBL ID
PubChem ID
InChIKey
AAOVKJBEBIDNHE-UHFFFAOYSA-N
SMILES
CN1c2ccc(cc2C(=NCC1=O)c3ccccc3)Cl
Drug Action
positive allosteric modulator
Affinity Metrics
ki:12 nM
kd:36 nM
ec50:85 nM