5-({(1R,1aS,6bR)-1-[5-(trifluoromethyl)-1H-benzimidazol-2-yl]-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-5-yl}oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one

P15056 — Serine/threonine-protein kinase B-raf

Attributes

UniProt ID

Protein Name

Serine/threonine-protein kinase B-raf

Ligand Name

5-({(1R,1aS,6bR)-1-[5-(trifluoromethyl)-1H-benzimidazol-2-yl]-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-5-yl}oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one

DrugBank ID

PDB Ligand Accession

ChEMBL ID

PubChem ID

InChIKey

NGFFVZQXSRKHBM-FKBYEOEOSA-N

SMILES

c1cc2c(cc1C(F)(F)F)nc([nH]2)C3C4C3Oc5c4cc(cc5)Oc6ccnc7c6CCC(=O)N7

Drug Action

inhibitor

Affinity Metrics