DrugDomain logoDrugDomain

2[4-BROMO-2-FLUOROPHENYL)METHYL]-6-FLUOROSPIRO[ISOQUINOLINE-4-(1H),3'-PYRROLIDINE]-1,2',3,5'(2H)-TETRONE

P15121 — Aldo-keto reductase family 1 member B1

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Attributes

UniProt ID
P15121
Protein Name
Aldo-keto reductase family 1 member B1
Ligand Name
2[4-BROMO-2-FLUOROPHENYL)METHYL]-6-FLUOROSPIRO[ISOQUINOLINE-4-(1H),3'-PYRROLIDINE]-1,2',3,5'(2H)-TETRONE
DrugBank ID
DB07450
PDB Ligand Accession
BFI
ChEMBL ID
CHEMBL292963
PubChem ID
447950
InChIKey
BMHZAHGTGIZZCT-LJQANCHMSA-N
SMILES
c1cc2c(cc1F)C3(CC(=O)NC3=O)C(=O)N(C2=O)Cc4ccc(cc4F)Br
Drug Action
n/a
Affinity Metrics
ic50:12.2 nM