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4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid

P19793 — Retinoic acid receptor RXR-alpha

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Attributes

UniProt ID
P19793
Protein Name
Retinoic acid receptor RXR-alpha
Ligand Name
4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid
DrugBank ID
DB00307
PDB Ligand Accession
9RA
ChEMBL ID
CHEMBL1023
PubChem ID
82146
InChIKey
NAVMQTYZDKMPEU-UHFFFAOYSA-N
SMILES
Cc1cc2c(cc1C(=C)c3ccc(cc3)C(=O)O)C(CCC2(C)C)(C)C
Drug Action
agonist
Affinity Metrics
ki:14 nM
ic50:632 nM
kd:7 nM
ec50:2.7 nM