Donepezil

P22303 — Acetylcholinesterase

Attributes

UniProt ID

Protein Name

Acetylcholinesterase

Ligand Name

Donepezil

DrugBank ID

PDB Ligand Accession

n/a

ChEMBL ID

n/a

PubChem ID

n/a

InChIKey

n/a

SMILES

COC1=C(OC)C=C2C(=O)C(CC3CCN(CC4=CC=CC=C4)CC3)CC2=C1

Drug Action

inhibitor

Affinity Metrics

ki:2.9 nM

ic50:2 nM

kd:8 nM

ec50:43 nM