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Macitentan

P24530 — Endothelin receptor type B

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Attributes

UniProt ID
P24530
Protein Name
Endothelin receptor type B
Ligand Name
Macitentan
DrugBank ID
DB08932
PDB Ligand Accession
A1D5I
ChEMBL ID
CHEMBL2103873
PubChem ID
16004692
InChIKey
JGCMEBMXRHSZKX-UHFFFAOYSA-N
SMILES
CCCNS(=O)(=O)Nc1c(c(ncn1)OCCOc2ncc(cn2)Br)c3ccc(cc3)Br
Drug Action
antagonist
Affinity Metrics
ic50:391 nM