DrugDomain logoDrugDomain

(4-AMINO-2-{[1-(METHYLSULFONYL)PIPERIDIN-4-YL]AMINO}PYRIMIDIN-5-YL)(2,3-DIFLUORO-6-METHOXYPHENYL)METHANONE

P24941 — Cyclin-dependent kinase 2

← Back

Attributes

UniProt ID
P24941
Protein Name
Cyclin-dependent kinase 2
Ligand Name
(4-AMINO-2-{[1-(METHYLSULFONYL)PIPERIDIN-4-YL]AMINO}PYRIMIDIN-5-YL)(2,3-DIFLUORO-6-METHOXYPHENYL)METHANONE
DrugBank ID
DB08094
PDB Ligand Accession
LIA
ChEMBL ID
CHEMBL384304
PubChem ID
6918852
InChIKey
JRNJNYBQQYBCLE-UHFFFAOYSA-N
SMILES
COc1ccc(c(c1C(=O)c2cnc(nc2N)NC3CCN(CC3)S(=O)(=O)C)F)F
Drug Action
inhibitor
Affinity Metrics
ki:3 nM
kd:0.53 nM