DrugDomain logoDrugDomain

2-[3,5-bis(trifluoromethyl)phenyl]-~{N},2-dimethyl-~{N}-[4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin-3-yl]propanamide

P25103 — Substance-P receptor

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Attributes

UniProt ID
P25103
Protein Name
Substance-P receptor
Ligand Name
2-[3,5-bis(trifluoromethyl)phenyl]-~{N},2-dimethyl-~{N}-[4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin-3-yl]propanamide
DrugBank ID
DB09048
PDB Ligand Accession
GAW
ChEMBL ID
CHEMBL206253
PubChem ID
6451149
InChIKey
WAXQNWCZJDTGBU-UHFFFAOYSA-N
SMILES
Cc1ccccc1c2cc(ncc2N(C)C(=O)C(C)(C)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)N4CCN(CC4)C
Drug Action
antagonist
Affinity Metrics
ki:0.95 nM
ic50:0.95 nM