DrugDomain logoDrugDomain

5-[[(2~{R},3~{S})-2-[(1~{R})-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one

P25103 — Substance-P receptor

← Back

Attributes

UniProt ID
P25103
Protein Name
Substance-P receptor
Ligand Name
5-[[(2~{R},3~{S})-2-[(1~{R})-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one
DrugBank ID
DB00673
PDB Ligand Accession
GBQ
ChEMBL ID
CHEMBL1471
PubChem ID
135413536; 6918365
InChIKey
ATALOFNDEOCMKK-OITMNORJSA-N
SMILES
CC(c1cc(cc(c1)C(F)(F)F)C(F)(F)F)OC2C(N(CCO2)CC3=NC(=O)NN3)c4ccc(cc4)F
Drug Action
antagonist
Affinity Metrics
ki:0.0794 nM
ic50:0.09 nM