2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl}methyl)benzonitrile

P27487 — Dipeptidyl peptidase 4

Attributes

UniProt ID

Protein Name

Dipeptidyl peptidase 4

Ligand Name

2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl}methyl)benzonitrile

DrugBank ID

PDB Ligand Accession

ChEMBL ID

PubChem ID

InChIKey

ZSBOMTDTBDDKMP-OAHLLOKOSA-N

SMILES

CN1C(=O)C=C(N(C1=O)Cc2ccccc2C#N)N3CCCC(C3)N

Drug Action

inhibitor

Affinity Metrics

ic50:0.9 nM

kd:2.4 nM