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4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one

P28335 — 5-hydroxytryptamine receptor 2C

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Attributes

UniProt ID
P28335
Protein Name
5-hydroxytryptamine receptor 2C
Ligand Name
4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
DrugBank ID
DB00502
PDB Ligand Accession
GMJ
ChEMBL ID
CHEMBL54
PubChem ID
3559
InChIKey
LNEPOXFFQSENCJ-UHFFFAOYSA-N
SMILES
c1cc(ccc1C(=O)CCCN2CCC(CC2)(c3ccc(cc3)Cl)O)F
Drug Action
antagonist
Affinity Metrics
ki:35.71 nM
ic50:10000 nM