DrugDomain logoDrugDomain

5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE

P28482 — Mitogen-activated protein kinase 1

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Attributes

UniProt ID
P28482
Protein Name
Mitogen-activated protein kinase 1
Ligand Name
5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE
DrugBank ID
DB07794
PDB Ligand Accession
FRZ
ChEMBL ID
CHEMBL259551
PubChem ID
11493598; 53338808
InChIKey
XVECMUKVOMUNLE-UHFFFAOYSA-N
SMILES
c1ccc(cc1)c2c(c3ccccn3n2)c4cc5c(n[nH]c5nn4)N
Drug Action
inhibitor
Affinity Metrics
ki:310 nM
ic50:1200 nM
kd:850 nM