DrugDomain logoDrugDomain

(5S)-2-{[(1S)-1-(2-fluorophenyl)ethyl]amino}-5-methyl-5-(trifluoromethyl)-1,3-thiazol-4(5H)-one

P28845 — 11-beta-hydroxysteroid dehydrogenase 1

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Attributes

UniProt ID
P28845
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Ligand Name
(5S)-2-{[(1S)-1-(2-fluorophenyl)ethyl]amino}-5-methyl-5-(trifluoromethyl)-1,3-thiazol-4(5H)-one
DrugBank ID
DB07310
PDB Ligand Accession
A21
ChEMBL ID
CHEMBL218006
PubChem ID
135513268; 16105493
InChIKey
KNHNFKZUNFPPQE-MADCSZMMSA-N
SMILES
CC(c1ccccc1F)NC2=NC(=O)C(S2)(C)C(F)(F)F
Drug Action
n/a
Affinity Metrics
ki:22 nM