N-{1-[(1-carbamoylcyclopropyl)methyl]piperidin-4-yl}-N-cyclopropyl-4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]benzamide

P28845 — 11-beta-hydroxysteroid dehydrogenase 1

Attributes

UniProt ID

Protein Name

11-beta-hydroxysteroid dehydrogenase 1

Ligand Name

N-{1-[(1-carbamoylcyclopropyl)methyl]piperidin-4-yl}-N-cyclopropyl-4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]benzamide

DrugBank ID

PDB Ligand Accession

ChEMBL ID

PubChem ID

InChIKey

FAVXIEFZKPJZRT-NRFANRHFSA-N

SMILES

CC(c1ccc(cc1)C(=O)N(C2CC2)C3CCN(CC3)CC4(CC4)C(=O)N)(C(F)(F)F)O

Drug Action

n/a

Affinity Metrics

ic50:14 nM