1-{[(3R)-3-methyl-4-({4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]phenyl}sulfonyl)piperazin-1-yl]methyl}cyclopropanecarboxamide

P28845 — 11-beta-hydroxysteroid dehydrogenase 1

Attributes

UniProt ID

Protein Name

11-beta-hydroxysteroid dehydrogenase 1

Ligand Name

1-{[(3R)-3-methyl-4-({4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]phenyl}sulfonyl)piperazin-1-yl]methyl}cyclopropanecarboxamide

DrugBank ID

PDB Ligand Accession

ChEMBL ID

PubChem ID

InChIKey

YJFULAYRAKPBCY-DYVFJYSZSA-N

SMILES

CC1CN(CCN1S(=O)(=O)c2ccc(cc2)C(C)(C(F)(F)F)O)CC3(CC3)C(=O)N

Drug Action

n/a

Affinity Metrics

ki:1.1 nM

ic50:0.7 nM