(1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile

P31645 — Sodium-dependent serotonin transporter

Attributes

UniProt ID

Protein Name

Sodium-dependent serotonin transporter

Ligand Name

(1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile

DrugBank ID

PDB Ligand Accession

ChEMBL ID

PubChem ID

InChIKey

WSEQXVZVJXJVFP-FQEVSTJZSA-N

SMILES

CN(C)CCCC1(c2ccc(cc2CO1)C#N)c3ccc(cc3)F

Drug Action

inhibitor

Affinity Metrics

ki:1 nM

ic50:2.1 nM

kd:2.6 nM

ec50:5100 nM