DrugDomain logoDrugDomain

1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[PIPERIDINE-4,2'(1'H)-QUINAZOLINE]-4'-AMINE

P35228 — Nitric oxide synthase, inducible

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Attributes

UniProt ID
P35228
Protein Name
Nitric oxide synthase, inducible
Ligand Name
1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[PIPERIDINE-4,2'(1'H)-QUINAZOLINE]-4'-AMINE
DrugBank ID
DB07405
PDB Ligand Accession
B14
ChEMBL ID
CHEMBL447183
PubChem ID
9886249
InChIKey
GIZYIOOBBUHOBS-UHFFFAOYSA-N
SMILES
c1cc(ncc1C(=O)N2CCC3(CC2)Nc4c(ccc(c4C(=N3)N)F)F)C#N
Drug Action
inhibitor
Affinity Metrics
ic50:35 nM