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(3E)-3-[(2,4-DIMETHOXYPHENYL)METHYLIDENE]-3,4,5,6-TETRAHYDRO-2,3'-BIPYRIDINE

P36544 — Neuronal acetylcholine receptor subunit alpha-7

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Attributes

UniProt ID
P36544
Protein Name
Neuronal acetylcholine receptor subunit alpha-7
Ligand Name
(3E)-3-[(2,4-DIMETHOXYPHENYL)METHYLIDENE]-3,4,5,6-TETRAHYDRO-2,3'-BIPYRIDINE
DrugBank ID
DB05708
PDB Ligand Accession
ZY7
ChEMBL ID
CHEMBL134713
PubChem ID
5310985
InChIKey
RPYWXZCFYPVCNQ-RVDMUPIBSA-N
SMILES
COc1ccc(c(c1)OC)C=C2CCCN=C2c3cccnc3
Drug Action
agonist
Affinity Metrics
kd:158 nM
ec50:1995.26 nM