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4-(3-PYRIDIN-2-YL-1H-PYRAZOL-4-YL)QUINOLINE

P36897 — TGF-beta receptor type-1

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Attributes

UniProt ID
P36897
Protein Name
TGF-beta receptor type-1
Ligand Name
4-(3-PYRIDIN-2-YL-1H-PYRAZOL-4-YL)QUINOLINE
DrugBank ID
DB03921
PDB Ligand Accession
PY1
ChEMBL ID
CHEMBL261454
PubChem ID
447966
InChIKey
IBCXZJCWDGCXQT-UHFFFAOYSA-N
SMILES
c1ccc2c(c1)c(ccn2)c3c[nH]nc3c4ccccn4
Drug Action
inhibitor
Affinity Metrics
ic50:27 nM
kd:5 nM
ec50:40 nM